Injection pen

Be sure to carefully review the precautions before use：Conditions in which use is not recommended1.Patients with hypoglycemia2.Pregnant women: Due to the long half-life, the medication should be discontinued at least 2 months before planning pregnancy.3.Nursing women4.Not recommended for children under 18 years of age5.If pancreatitis is suspected, discontinue the medication. If pancreatitis is confirmed, do not use this medication for treatment. Use with caution in patients with a history of pancreatitis.6.Not for the treatment of type 1 diabetes or diabetic ketoacidosis.7.Patients with a personal or family history of medullary thyroid carcinoma.8.Patients with type 2 multiple endocrine neoplasia syndrome.In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of Losasio® in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of semaglutide injection in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abiraterone Acetate
• Acarbose
• Chloroquine
• Chlorpropamide
• Ciprofloxacin
• Delafloxacin
• Enoxacin
• Gatifloxacin
• Gemifloxacin
• Glimepiride
• Glipizide
• Glyburide
• Grepafloxacin
• Hydroxychloroquine
• Insulin
• Insulin Aspart, Recombinant
• Insulin Bovine
• Insulin Degludec
• Insulin Detemir
• Insulin Glulisine
• Insulin Lispro, Recombinant
• Levofloxacin
• Lomefloxacin
• Metformin
• Moxifloxacin
• Nateglinide
• Norfloxacin
• Ofloxacin
• Repaglinide
• Somatrogon-ghla
• Sparfloxacin
• Tolazamide
• Tolbutamide
• Trovafloxacin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Albiglutide
• Dulaglutide
• Exenatide
• Glecaprevir
• Liraglutide
• Lixisenatide
• Pibrentasvir
• Tirzepatide

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Depression, history of or
• Diabetic retinopathy, history of or
• Digestion problems or
• Kidney disease or
• Type 2 diabetes (for patients using Losasio®)—Use with caution. May make these conditions worse.Diabetic ketoacidosis (ketones in the blood) or
• Type 1 diabetes—Should not be used in patients with these conditions. Insulin is needed to control these conditions.
• Multiple endocrine neoplasia syndrome type 2 (MEN 2) or
• Thyroid cancer, history of—Should not be used in patients with these conditions.
• Pancreatitis (inflammation of the pancreas), history of—It is not known if this medicine will be safe in patients with this condition.

Transportation Guidelines for Semaglutide (Losasio)

Transportation Method: Cold Chain TransportOverview: To ensure the integrity and efficacy of Semaglutide (Losasio) during transportation, it is crucial to adhere to strict cold chain guidelines. The following precautions must be observed:1. Temperature Control:

• Maintain a consistent temperature range of 2°C to 8°C (36°F to 46°F) throughout the entire transportation process.
• Utilize temperature-controlled containers or refrigerated vehicles specifically designed for cold chain logistics.

2. Monitoring:

• Implement temperature monitoring devices to continuously track the temperature during transit.
• Record temperature data at regular intervals to ensure compliance with required conditions.

3. Packaging:

• Use insulated packaging materials that provide effective temperature control.
• Ensure that the product is securely packed to prevent movement or damage during transportation.
• Include gel packs or dry ice if necessary to maintain the required temperature range.

4. Handling Procedures:

• Train personnel involved in the handling and transportation of Semaglutide on proper cold chain protocols.
• Avoid exposure to ambient temperatures for extended periods during loading and unloading.

5. Emergency Protocols:

• Establish emergency procedures for handling temperature excursions (e.g., if the temperature exceeds the required range).
• In case of a temperature breach, assess the integrity of the product before delivery.

6. Documentation:

• Include documentation with the shipment that specifies the temperature requirements and monitoring details.
• Ensure that all relevant shipping and handling records are maintained for accountability.

7. Delivery:

• Aim for prompt delivery to minimize the time the product spends outside the controlled temperature range.
• Communicate with the receiving party to ensure readiness to receive the shipment under proper conditions.

Conclusion: Adhering to these cold chain transportation guidelines is essential to maintain the quality and effectiveness of Semaglutide (Losasio). Proper planning and execution of cold chain logistics will help ensure patient safety and treatment efficacy.

Thank you for choosing Losasio for your health management. In order to ensure the quality and safety of drugs, and to ensure the stability and compliance of the drug supply chain, we hereby formulate the following return and exchange policy. Please read the terms of this policy carefully before purchasing and confirm that you have understood and agreed to these terms.

1. Overview of Return and Exchange Policy

Semaglutide is a prescription drug. Due to strict requirements for drug safety and quality control, we do not accept any return or exchange requests due to non-quality issues (such as personal reasons, unsatisfactory efficacy, mispurchase, etc.). Please be sure to carefully confirm the type, specification and quantity of the drug before purchasing.

2. Scope of application

This return and exchange policy applies to all semaglutide products purchased through official authorized channels, including but not limited to:

• Drug specifications: semaglutide injection of all doses and packaging specifications.
• Purchase channels: All products purchased through regular pharmacies, hospitals and authorized online pharmacies.

3. Return and Exchange Conditions

Quality Issues:

If you find that the drug packaging is damaged, the drug is expired, the appearance is obviously abnormal, or other quality issues do exist after receiving the product, please contact the customer service department of the purchase channel within 7 days after receiving the product and provide the following materials:

• Purchase Proof (such as receipt, invoice, etc.)
• Photos of the drug packaging and detailed description of the quality problem
• Related doctor's prescription (if applicable)
• After verification and confirmation of the quality problem, we will provide you with return and exchange services.

Non-quality issues:

• Based on the particularity and safety of the drug, any return or exchange request due to personal reasons (such as dissatisfaction with the efficacy, change of treatment plan, wrong purchase, etc.) will not be accepted.
• After purchase, once the drug is issued, it is deemed to have been used for the patient's personal health management and cannot be restocked or resold, so it is not accepted for return and exchange.

4. Return and Exchange Process

Quality Issue Return and Exchange Process:

• Contact Customer Service: Please contact the customer service department of the purchase channel within 7 days after discovering the problem.
• Provide information: Provide purchase receipts, drug photos and problem descriptions as required.
• Processing time: The customer service team will verify the problem and contact you within 3 working days after receiving complete information to confirm the specific arrangements for return and exchange.
• Return and exchange method: Depending on the nature of the problem, you may be asked to return the problematic drug. The return postage will be reimbursed after the quality problem is confirmed.

Refund and exchange arrangements:

• If the return is confirmed, we will process the refund within 7 working days after receiving the returned drug, and the refund will be returned to the original payment method.
• If the exchange is confirmed, we will re-ship within 7 working days after confirmation.

5. Precautions

• Drug storage and use:Please store and use strictly in accordance with the doctor's advice and the requirements in the drug instructions. Damage or expiration of drugs caused by improper storage or use are not within the scope of return and exchange.
• Complaints and suggestions: If you have any questions about this return and exchange policy or need further help, please contact the customer service department of the purchase channel or obtain support through the customer service hotline provided by the manufacturer.

6. Right of interpretation of the policy

The final right of interpretation of this policy belongs to the seller of semaglutide. We reserve the right to modify and update this policy in accordance with laws, regulations and business needs. Any changes will be notified in advance and will apply to all transactions from the date of the notification.This policy details the applicable conditions, procedures and precautions for the return and exchange of semaglutide, and clarifies the provisions that no return or exchange will be made unless there is a quality issue, ensuring that users understand and agree to these terms before purchasing.